Colloid-chemical aspects of protein crystallization
Identifieur interne : 002153 ( Main/Exploration ); précédent : 002152; suivant : 002154Colloid-chemical aspects of protein crystallization
Auteurs : V. G. Kulichikhin [Russie] ; G. P. Yampolskaya [Russie]Source :
- Russian Chemical Bulletin [ 1066-5285 ] ; 2013-02-01.
English descriptors
Abstract
Abstract: Problems and prospects of the crystallization of water-soluble and membrane proteins are discussed. The main focus is on colloid-chemical aspects of crystallization processes and the use of surfactants and various structured dispersions (surfactant-based gels and lyotropic phases). Advantages of the protein crystallization on solid supports of different nature, including biopolymer supports, are considered. Apparently, we are witnesses to the rise of a new field, nanocrystallography, dealing with the determination of protein structures from the investigation of nanocrystals.
Url:
DOI: 10.1007/s11172-013-0045-x
Affiliations:
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<front><div type="abstract" xml:lang="en">Abstract: Problems and prospects of the crystallization of water-soluble and membrane proteins are discussed. The main focus is on colloid-chemical aspects of crystallization processes and the use of surfactants and various structured dispersions (surfactant-based gels and lyotropic phases). Advantages of the protein crystallization on solid supports of different nature, including biopolymer supports, are considered. Apparently, we are witnesses to the rise of a new field, nanocrystallography, dealing with the determination of protein structures from the investigation of nanocrystals.</div>
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